Chlamydia is usually detected by PCR testing of first-catch urine or samples taken by urogenital swab. The sensitivity of this test may be less than optimal if the infection is situated in the uterine cervix. Conversely, some infected women may harbor Chlamydia only in their urethra, which can increase the chance of misdetection from specimens taken endocervically or by vaginal swab. With this in mind, we can say with confidence that testing on single specimens can fail to identify all infected women.

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